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Boehringer’s Survodutide Shows Breakthrough Improvement in MASH Trial

Builds on previously announced primary endpoint, which showed up to 83% of adults achieved statistically significant improvement in MASH versus placebo.

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By: Kristin Brooks

Managing Editor, Contract Pharma

Boehringer Ingelheim announced breakthrough results from a survodutide Phase II trial sub-analysis that demonstrate up to 64.5% of adults with fibrosis stages F2 and F3 (moderate to advanced scarring) achieved an improvement in fibrosis without worsening of metabolic dysfunction-associated steatohepatitis (MASH), versus 25.9% with placebo after 48 weeks of treatment. F2 and F3 patient populations are at increased risk of developing liver-related complications. The secondary endpoint shows th...

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